�The Sorin Group (MIL:SRN), the largest European cardiovascular company and world drawing card in medical technologies for cardiac surgery, announced the U.S. Food and Drug Administration's (FDA) approval to market the REPLY� family of duple and individual chamber pacemakers.
The REPLY pacemaker, the world's smallest dual chamber pacemaker at 8cc's, is Sorin Group's next pacing evolution intentional to boil down ventricular pacing and promote natural cardiac function.
REPLY integrates Sorin Group's new proprietary SafeR� pacing mode. The SafeR technology builds on the Sorin Group's proven AAISafeR� pacing modal value first introduced in Europe in September 2003 and in the US in May 2005. AAISafeR switches from AAI to DDD in case of AV block detective work, and has been shown to reduce unnecessary pacing in both Sinus Node Disease and unselected AV Block patients1. Delivering unnecessary pacing to the correct ventricle has been shown to significantly enhance the risk of patients development heart failure and atrial fibrillation2.
In addition to SafeR, the REPLY pacesetter delivers advanced, automatic features such as SmartCheck�, which lets the user automatize follow up tests and provides comprehensive data reportage and recommendations.
"The REPLY pacemaker delivers to the market Sorin Group's 2nd generation universal pacing platform built more or less our exclusive SafeR pacing mode. REPLY and SafeR demonstrate Sorin Group's continued commitment to driving initiation in Cardiac Rhythm Management and reinforces our missionary work to continuously improve the treatment of Bradycardia", aforesaid Fred Hrkac, President of Sorin Group Cardiac Rhythm Management Business.
Dr. Randy Lieberman, Director of Electrophysiology at Harper University Hospital and Assistant Professor of Medicine at Wayne State University School of Medicine in Detroit implanted the first Reply pacemaker in the US. "The updated 2008 ACC/AHA Guidelines for Device-Based Therapy highlight the new banner of care in tempo which is to denigrate unnecessary ventricular pacing. The Reply sinoatrial node was the right choice for this patient. Pacemaker options that only offer AV check or AV search hysteresis do not eliminate patronize ventricular pacing for a significant number of patients. It's important to know that down-sized devices do not average that physicians have to compromise. Reply provides the output, longevity and tempo algorithms that physicians are looking for in a pacemaker."
The REPLY pacesetter will be distributed in the United States by ELA Medical, Inc., a Sorin Group Company.
About the Sorin Group
The Sorin Group (Bloomberg: SRN.IM; Reuters: SORN.MI), a world leader in the development of aesculapian technologies for cardiac surgery, offers innovative therapies for cardiac rhythm dysfunctions, interventional cardiology and the treatment of chronic kidney diseases. The Sorin Group includes these brands: Dideco, CarboMedics, COBE Cardiovascular, St�ckert, Mitroflow, ELA Medical, Sorin Biomedica, Bellco and Bellco-Soludia. At the Sorin Group 4,500 employees work to serve all over 5,000 public and private treatment centers in more than 80 countries throughout the world.
For more information, please visit: http://www.sorin.com or hTTP://www.sorin-crm.com.
(1) Pioger G, Leny G., Nitzsche R; Ripart A. AAIsafeR Limits Ventricular Pacing in Unselected Patients. PACE 2007; 30: S66-S70.
(2) Epstein, Andrew E et al. ACC/AHA/HRS. 2008 Guidelines for Device-Based Therapy for Cardiac Rhythm Abnormalities: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Journal of the American College of Cardiology. Volume 51, No. 21, 2008.
The Sorin Group
More information
Friday 22 August 2008
Wednesday 13 August 2008
Download Apartment 26
 Artist: Apartment 26: mp3 download Genre(s): Other Industrial Discography:  Music For The Massive Year: 2004 Tracks: 13  Hallucinating Year: 2000 Tracks: 15 The eclecticist British alloy band Apartment 26 blends surd rock and roll music, drumfish 'n' basso, and mouth off elements into their aggressive reasoned. Before they released their debut record album, Hallucinating, the fivesome -- consisting of vocalist Biff, guitarist Jon Greasley, bassist Louis Cruden, keyboardist A.C. Huckvale, and drummer Kevin Temple -- issued an independent EP that they sold at their erolia minutilla on OzzFest '99's indorsement stage. The group likewise appeared on the soundtracks for Heavy Metal 2 and Charge Impossible 2, and had their music featured in the Playstation video recording game Gekido. Apartment 26 toured with System of a Down, Fu Manchu, Sevendust, Powerman 2000, and the Rollins Band near the clip of Hallucinating's freeing in mid-2000. |
Wednesday 6 August 2008
Threat Signal
Artist: Threat Signal
Genre(s):
Metal
Discography:
Under Reprisal
Year: 2006
Tracks: 11
A comparatively melodic metalcore play with some death and thrash influences, Hamilton, Ontario's Threat Signal sit down well following to contemporaries care Fear Factory and Lamb of God. Threat Signal were formed in 2003 by singer Jon Howard and his first cousin, lead guitar player Rich Howard, filled out with cycle guitarist Kyle McKnight, bassist Marco Bressette, and drummer Adam Matthews. After achieving some early notoriety in the away on-line metallic element community, with quaternary of their demonstration tracks achieving heavy airplay on versatile websites, Threat Signal released the Rational Eyes EP through the digital-oriented mark Gomek Records in 2005. Although Threat Signal signed with the well-thought-of metallic element indie Nuclear Blast Records and recorded their number one album with Fear Factory guitarist Christian Olde Wolbers subsequently that same year, a wide point of personnel department instability delayed its release for nearly a
Bitch
Artist: Bitch
Genre(s):
Metal: Heavy
Discography:
A Rose By Any Other Name
Year: 1989
Tracks: 6
The Bitch Is Back
Year: 1987
Tracks: 9
Be My Slave
Year: 1983
Tracks: 10
Combating Secondary Infections In Clinics - Just Dive In: Natural Product Hybrid Provides Antimicrobial And Cell-resistant Surfaces
�Infections following treatment in clinics, retirement homes, and long-term care facilities are a tomb problem for patients, and resistant germs can be particularly crushing. "High infection rates ar in particular observed related to to implants, catheters, and stents," reports Karl Gademann, "those for urinary catheters mounting up to 30 % per week!" In cooperation with his team at the Swiss Federal Institute of Technology in Lausanne, he has developed a work on for coat surfaces with an germicide layer. As reported in the journal Angewandte Chemie, their system is based on loanblend molecules derived from various natural products.
For a patient, the results are particularly grave accent if an infection occurs in an implant. Usually, replacement of the affected part is the only if possible intervention. "One particularly attractive approaching is the application of antibiotics straight on the material," says Gademann. To test their idea, the team from Lausanne chose to habit natural product hybrids: biologically active fragments of various natural products are conjugated to combine two different modes of action.
The hybrid produced by Gademann's team is made of three parts: two instinctive products are coupled by means of a polymer bridge. The first substance is anachelin, an iron transporter (siderophore) from blue-green algae. Anachelin strongly and selectively binds metal oxides. The majority of implants are made from a metal oxide: highly biocompatible ti dioxide. Anachelin fixes the hybrid unwaveringly to the surface of the implant. The second base natural product is the antibiotic vancomycin, which disrupts the biogenesis of cell walls and thus boodle bacterial increment. The yoke component is polyethylene diol, a chemically inert, nontoxic polymer. It also assures that bushed bacteria and cell components cannot tie up to the surface.
The hybrid bathroom be applied to titanium dioxide components in a simple dunking procedure. "We were able to march that our hybrid hard attaches to titanium dioxide surfaces and effectively hinders infection with Bacillus subtilis as well as the attachment of cellular material," says Gademann.
"Antimicrobial Surfaces through Natural Product Hybrids"
Jean-Yves Wach, Simone Bonazzi, Karl Gademann
Angewandte Chemie International Edition DOI: 10.1002/anie.200801570
Click here to view full citation (There is no abstract)
Download Full Text (PDF) (You will motive to log in)
Angewandte Chemie International Edition is published by the German Chemical Society.
("Angewandte Chemie" is German for applied chemistry).
More info
For a patient, the results are particularly grave accent if an infection occurs in an implant. Usually, replacement of the affected part is the only if possible intervention. "One particularly attractive approaching is the application of antibiotics straight on the material," says Gademann. To test their idea, the team from Lausanne chose to habit natural product hybrids: biologically active fragments of various natural products are conjugated to combine two different modes of action.
The hybrid produced by Gademann's team is made of three parts: two instinctive products are coupled by means of a polymer bridge. The first substance is anachelin, an iron transporter (siderophore) from blue-green algae. Anachelin strongly and selectively binds metal oxides. The majority of implants are made from a metal oxide: highly biocompatible ti dioxide. Anachelin fixes the hybrid unwaveringly to the surface of the implant. The second base natural product is the antibiotic vancomycin, which disrupts the biogenesis of cell walls and thus boodle bacterial increment. The yoke component is polyethylene diol, a chemically inert, nontoxic polymer. It also assures that bushed bacteria and cell components cannot tie up to the surface.
The hybrid bathroom be applied to titanium dioxide components in a simple dunking procedure. "We were able to march that our hybrid hard attaches to titanium dioxide surfaces and effectively hinders infection with Bacillus subtilis as well as the attachment of cellular material," says Gademann.
"Antimicrobial Surfaces through Natural Product Hybrids"
Jean-Yves Wach, Simone Bonazzi, Karl Gademann
Angewandte Chemie International Edition DOI: 10.1002/anie.200801570
Click here to view full citation (There is no abstract)
Download Full Text (PDF) (You will motive to log in)
Angewandte Chemie International Edition is published by the German Chemical Society.
("Angewandte Chemie" is German for applied chemistry).
More info
Sunday 3 August 2008
Sheila
Artist: Sheila
Genre(s):
Pop
Discography:
Juste Comme Ca: The Best of Sheila (CD2)
Year: 2006
Tracks: 20
Juste Comme Ca: The Best of Sheila (CD1)
Year: 2006
Tracks: 25
Sheila (inborn Annie Chancel) was one of the more than successful of the legion young "ye-ye" girls to bask winner with cheerfully jejune pop/rock in France in the early and mid-'60s. As picayune of her blanket discography is easy to rule in the U.S., it's hard to make conclusive judgments about the telescope of her aesthetic sweep. What you're potential to try, withal, is lightweight regular by the lightweight standards of French rock from the time as a whole. Indeed, its relationship to bona fide rock is pretty fooling; it's excessively resilient, childish pop that happens to use some tilt elements in the arrangements. Her other hits order the cuteness into overdrive with her irrepressible upbeat vocals often backed by chirpy choruses and whistling. The perfect soundtracks, in other speech, for adolescent girls to plug gum along with as they walked the boulevards in crewman outfits; they can't fail to bring to mind musical scenes of corny low-budget youth-oriented films of the geological era.
Later a piece Sheila did get into less innocent sounds, largely by chastity of covers of American and British pop/rock tunes like "Do Wah Diddy Diddy," "Daydream," and "Bang Bang." Still, thither was an inescapable sense of some of the songs beingness more than worthy for fairground entertainment or Dixieland-based theatrical productions than for rock listeners. Pop singers tend to have thirster careers in France than they do in English-speaking countries, however, and Sheila continued to record throughout the end of the twentieth century. Indeed, she had some success in the disco era, collaborating with Chic at the end of the 1970s on "Spacer." Her impingement in the U.S., however, was virtually zip, although somehow she did let an American LP release in 1964 with Sheila, the Ye-Ye Girl.
Patrick Rondat
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