Sorin Group Announces FDA Approval And First U.S. Implant Of The World's Smallest Implantable Dual Chamber Pacemaker

�The Sorin Group (MIL:SRN), the largest European cardiovascular company and world drawing card in medical technologies for cardiac surgery, announced the U.S. Food and Drug Administration's (FDA) approval to market the REPLY� family of duple and individual chamber pacemakers.


The REPLY pacemaker, the world's smallest dual chamber pacemaker at 8cc's, is Sorin Group's next pacing evolution intentional to boil down ventricular pacing and promote natural cardiac function.


REPLY integrates Sorin Group's new proprietary SafeR� pacing mode. The SafeR technology builds on the Sorin Group's proven AAISafeR� pacing modal value first introduced in Europe in September 2003 and in the US in May 2005. AAISafeR switches from AAI to DDD in case of AV block detective work, and has been shown to reduce unnecessary pacing in both Sinus Node Disease and unselected AV Block patients1. Delivering unnecessary pacing to the correct ventricle has been shown to significantly enhance the risk of patients development heart failure and atrial fibrillation2.


In addition to SafeR, the REPLY pacesetter delivers advanced, automatic features such as SmartCheck�, which lets the user automatize follow up tests and provides comprehensive data reportage and recommendations.


"The REPLY pacemaker delivers to the market Sorin Group's 2nd generation universal pacing platform built more or less our exclusive SafeR pacing mode. REPLY and SafeR demonstrate Sorin Group's continued commitment to driving initiation in Cardiac Rhythm Management and reinforces our missionary work to continuously improve the treatment of Bradycardia", aforesaid Fred Hrkac, President of Sorin Group Cardiac Rhythm Management Business.


Dr. Randy Lieberman, Director of Electrophysiology at Harper University Hospital and Assistant Professor of Medicine at Wayne State University School of Medicine in Detroit implanted the first Reply pacemaker in the US. "The updated 2008 ACC/AHA Guidelines for Device-Based Therapy highlight the new banner of care in tempo which is to denigrate unnecessary ventricular pacing. The Reply sinoatrial node was the right choice for this patient. Pacemaker options that only offer AV check or AV search hysteresis do not eliminate patronize ventricular pacing for a significant number of patients. It's important to know that down-sized devices do not average that physicians have to compromise. Reply provides the output, longevity and tempo algorithms that physicians are looking for in a pacemaker."


The REPLY pacesetter will be distributed in the United States by ELA Medical, Inc., a Sorin Group Company.

About the Sorin Group


The Sorin Group (Bloomberg: SRN.IM; Reuters: SORN.MI), a world leader in the development of aesculapian technologies for cardiac surgery, offers innovative therapies for cardiac rhythm dysfunctions, interventional cardiology and the treatment of chronic kidney diseases. The Sorin Group includes these brands: Dideco, CarboMedics, COBE Cardiovascular, St�ckert, Mitroflow, ELA Medical, Sorin Biomedica, Bellco and Bellco-Soludia. At the Sorin Group 4,500 employees work to serve all over 5,000 public and private treatment centers in more than 80 countries throughout the world.


For more information, please visit: http://www.sorin.com or hTTP://www.sorin-crm.com.


(1) Pioger G, Leny G., Nitzsche R; Ripart A. AAIsafeR Limits Ventricular Pacing in Unselected Patients. PACE 2007; 30: S66-S70.


(2) Epstein, Andrew E et al. ACC/AHA/HRS. 2008 Guidelines for Device-Based Therapy for Cardiac Rhythm Abnormalities: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Journal of the American College of Cardiology. Volume 51, No. 21, 2008.

The Sorin Group


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Download Apartment 26

Artist: Apartment 26: mp3 download    Genre(s):  Other Industrial     Discography:      Music For The Massive    Year: 2004    Tracks: 13      Hallucinating    Year: 2000    Tracks: 15 The eclecticist British alloy band Apartment 26 blends surd rock and roll music, drumfish 'n' basso, and mouth off elements into their aggressive reasoned. Before they released their debut record album, Hallucinating, the fivesome -- consisting of vocalist Biff, guitarist Jon Greasley, bassist Louis Cruden, keyboardist A.C. Huckvale, and drummer Kevin Temple -- issued an independent EP that they sold at their erolia minutilla on OzzFest '99's indorsement stage. The group likewise appeared on the soundtracks for Heavy Metal 2 and Charge Impossible 2, and had their music featured in the Playstation video recording game Gekido. Apartment 26 toured with System of a Down, Fu Manchu, Sevendust, Powerman 2000, and the Rollins Band near the clip of Hallucinating's freeing in mid-2000.

Threat Signal

   
Artist: Threat Signal

   Genre(s): 
Metal
   

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Discography:


   
 Under Reprisal

   Year: 2006   
Tracks: 11

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A comparatively melodic metalcore play with some death and thrash influences, Hamilton, Ontario's Threat Signal sit down well following to contemporaries care Fear Factory and Lamb of God. Threat Signal were formed in 2003 by singer Jon Howard and his first cousin, lead guitar player Rich Howard, filled out with cycle guitarist Kyle McKnight, bassist Marco Bressette, and drummer Adam Matthews. After achieving some early notoriety in the away on-line metallic element community, with quaternary of their demonstration tracks achieving heavy airplay on versatile websites, Threat Signal released the Rational Eyes EP through the digital-oriented mark Gomek Records in 2005. Although Threat Signal signed with the well-thought-of metallic element indie Nuclear Blast Records and recorded their number one album with Fear Factory guitarist Christian Olde Wolbers subsequently that same year, a wide point of personnel department instability delayed its release for nearly a

Counting Cards in Vegas

He'd never been to Vegas and he'd ne'er played

Bitch

   
Artist: Bitch

   Genre(s): 
Metal: Heavy
   

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Discography:


   
 A Rose By Any Other Name

   Year: 1989   
Tracks: 6


   
 The Bitch Is Back

   Year: 1987   
Tracks: 9


   
 Be My Slave

   Year: 1983   
Tracks: 10

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Combating Secondary Infections In Clinics - Just Dive In: Natural Product Hybrid Provides Antimicrobial And Cell-resistant Surfaces

�Infections following treatment in clinics, retirement homes, and long-term care facilities are a tomb problem for patients, and resistant germs can be particularly crushing. "High infection rates ar in particular observed related to to implants, catheters, and stents," reports Karl Gademann, "those for urinary catheters mounting up to 30 % per week!" In cooperation with his team at the Swiss Federal Institute of Technology in Lausanne, he has developed a work on for coat surfaces with an germicide layer. As reported in the journal Angewandte Chemie, their system is based on loanblend molecules derived from various natural products.


For a patient, the results are particularly grave accent if an infection occurs in an implant. Usually, replacement of the affected part is the only if possible intervention. "One particularly attractive approaching is the application of antibiotics straight on the material," says Gademann. To test their idea, the team from Lausanne chose to habit natural product hybrids: biologically active fragments of various natural products are conjugated to combine two different modes of action.


The hybrid produced by Gademann's team is made of three parts: two instinctive products are coupled by means of a polymer bridge. The first substance is anachelin, an iron transporter (siderophore) from blue-green algae. Anachelin strongly and selectively binds metal oxides. The majority of implants are made from a metal oxide: highly biocompatible ti dioxide. Anachelin fixes the hybrid unwaveringly to the surface of the implant. The second base natural product is the antibiotic vancomycin, which disrupts the biogenesis of cell walls and thus boodle bacterial increment. The yoke component is polyethylene diol, a chemically inert, nontoxic polymer. It also assures that bushed bacteria and cell components cannot tie up to the surface.


The hybrid bathroom be applied to titanium dioxide components in a simple dunking procedure. "We were able to march that our hybrid hard attaches to titanium dioxide surfaces and effectively hinders infection with Bacillus subtilis as well as the attachment of cellular material," says Gademann.

"Antimicrobial Surfaces through Natural Product Hybrids"

Jean-Yves Wach, Simone Bonazzi, Karl Gademann
Angewandte Chemie International Edition DOI: 10.1002/anie.200801570
Click here to view full citation (There is no abstract)
Download Full Text (PDF) (You will motive to log in)

Angewandte Chemie International Edition is published by the German Chemical Society.
("Angewandte Chemie" is German for applied chemistry).


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Sheila

   
Artist: Sheila

   Genre(s): 
Pop
   

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Discography:


   
 Juste Comme Ca: The Best of Sheila (CD2)

   Year: 2006   
Tracks: 20


   
 Juste Comme Ca: The Best of Sheila (CD1)

   Year: 2006   
Tracks: 25

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Sheila (inborn Annie Chancel) was one of the more than successful of the legion young "ye-ye" girls to bask winner with cheerfully jejune pop/rock in France in the early and mid-'60s. As picayune of her blanket discography is easy to rule in the U.S., it's hard to make conclusive judgments about the telescope of her aesthetic sweep. What you're potential to try, withal, is lightweight regular by the lightweight standards of French rock from the time as a whole. Indeed, its relationship to bona fide rock is pretty fooling; it's excessively resilient, childish pop that happens to use some tilt elements in the arrangements. Her other hits order the cuteness into overdrive with her irrepressible upbeat vocals often backed by chirpy choruses and whistling. The perfect soundtracks, in other speech, for adolescent girls to plug gum along with as they walked the boulevards in crewman outfits; they can't fail to bring to mind musical scenes of corny low-budget youth-oriented films of the geological era.


Later a piece Sheila did get into less innocent sounds, largely by chastity of covers of American and British pop/rock tunes like "Do Wah Diddy Diddy," "Daydream," and "Bang Bang." Still, thither was an inescapable sense of some of the songs beingness more than worthy for fairground entertainment or Dixieland-based theatrical productions than for rock listeners. Pop singers tend to have thirster careers in France than they do in English-speaking countries, however, and Sheila continued to record throughout the end of the twentieth century. Indeed, she had some success in the disco era, collaborating with Chic at the end of the 1970s on "Spacer." Her impingement in the U.S., however, was virtually zip, although somehow she did let an American LP release in 1964 with Sheila, the Ye-Ye Girl.





Patrick Rondat

Osbourne slams Moss' 'grumpy' boyfriend

Osbourne slams Moss' 'grumpy' boyfriend

Grace Kelly Osbourne is reportedly unimpressed by her admirer Kate Moss' young man Jamie Hince - dismissing the musician as "grumpy".
The reality TV asterisk advert the supermodel's 34th birthday in London last week where The Kills guitarist reportedly kept a low profile.
However, Osbourne, 23, insists the couple ar a goodness match, even though Hince has a trend to be negative.
Digitalspy quotes her as saying: "I call Jamie the grumpy old military man because he likes a good groan - but he and Kate do work well together."




Dame Edna told to rest after surgery

Winehouse's husband voted top 'Anti-Icon'

Winehouse's husband voted top 'Anti-Icon'

Amy Winehouse's hubby Blake Fielder-Civil has been voted Britain's top of the inning Anti-Icon.
Readers of men's mag Sports stadium compiled a lean of "witless" male celebrities wHO least deserve their place in the spot.
Fielder-Civil - currently on put behind bars in Pentonville Prison awaiting test - headed the Top 10.
Second base on the list was Banksy, the graffito artist world Health Organization counts Angelina Jolie and Jude Natural law among his fans.
England and Chelsea footballer Frank Lampard was third, accused of "weakness the country" with his lacklustre presentation in the Euro 2008 qualifiers.
Falsetto-voiced isaac Bashevis Singer Mika was fourth, followed by day TV host Jeremy Kyle.
St. Peter the Apostle Andre was one-sixth for forming "half of Britain's about over-exposed couple" with glamor model wife Jordan, and ex-'Big Brother' housemate Ziggy was seventh. Pop star Prince was eighth.
TV presenting duette Pismire and Dec were one-ninth and 'Top Gear's Richard Hammond was 10th.

Corrie's Vera speaks about illness

Corrie's Vera speaks about illness

Former 'Coronation Street' actress Liz Dawn has spoken some how her life has changed since she was diagnosed with pulmonary emphysema basketball team years ago.
The 68-year-old actress told ITV's 'Tonight' that she was told by doctors that she only had one third base of her lung capacity left.
Morning, world Health Organization played Vera Duckworth in 'Coronation Street', latterly leave office the show due to badly health.
She said: "I used to go to Granada and I used to go in the fertilization room, and I'd be really breathless before I even did anything."
"And I got that badly, at the end that rather of person knocking on the door and expression: 'It's your scene', I used to go on a setting earlier and sit around on the Duckworths' localise."
Dayspring besides said that she quit smoke later her diagnosis: "When you're addicted to smoking it's rattling hard to stop... I couldn't do the telephone unless I lit up."
The actress said that she regretted smoke around non-smokers: "I intend in that respect ar a lot of non-smokers in 'Coronation Street' that I have stood next to and smoked. Must have been awful mustn't it?"
Dawn's doctor Prof Ashley Woodcock said: "Liz came to me around v long time ago rattling fairly desperate."
"At that point she could walk just now a duo of yards... she was in a rattling bad means."
"Stopping her smoking was truly critical and she did that... which has been great because she wouldn't be here now... if she hadn't stopped"

Tate hints that Tennant may quit Dr Who

Tate hints that Tennant may quit Dr Who

Actress Catherine the Great John Orley Allen Tate has hinted that her 'Doctor Who' co-star St. David Tennant crataegus laevigata be set to depart the show.
The actress made the comments during an interview on Jonathan Ross' radio programme.
Tate, wHO stars as the doctor's supporter in series four-spot of the show, said: "I think it's maybe David's last series."
She likewise confirmed that the forthcoming series of 'Doctor Who' would be her last.
The BBC refused to comment on the suggestion that Tennant is go under to relinquish the show.

Johnny Depp to replace Ledger in final role?

Johnny Depp to replace Ledger in final role?

Greyback Depp english hawthorn be poised to put back the late

Misery Signals

   
Artist: Misery Signals

   Genre(s): 
ROck: Alternative
   

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Discography:


   
 Of Malice And The Magnum Heart

   Year: 2004   
Tracks: 10

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Post-hardcore act Misery Signals blend mathematics rock tropes care catchy cartridge clip touch shifts and twiddly guitar parts with the strained hostility and painful throat vocals of screamo, creating a sound with more emotional heft than the one time til now that is as well less monochromous than the latter. Misery Signals formed in Madison, WI, in 2003, featuring members of a number of regional hardcore and emo bands. Singer Jesse Zaraska had the highest profile, having worked with 7 Angels, 7 Plagues and the Canadian hardcore act Compromise, which had broken up in 2002 chase the last of deuce of its members in a cable car accident. Guitar player Jeff Aust had been in Hamartia, patch guitar player Ryan Thomas Hunt Morgan, bassist Kyle President Andrew Johnson, and drummer Branden Morgan (Ryan's brother) filled come out the card. Pursual the band's self-titled half a 12 cut EP, released in 2003, Aust was replaced by new guitar player





Rundfunkchor Leipzip, Staatskapelle Dresden

Nicole Richie says motherhood is “like nothing I could have imagined”

Nicole Richie says motherhood is “like nothing I could have imagined”

Nicole Richie is loving motherhood.
“It’s in spades like zip I could have imagined,” the socialite, 26, said at the the 25th Yearly ASCAP Bug out Music Awards in Los Angeles, where she appeared with begetter Lionel Richie.
Nicole goes on to say that life with daughter Jean Harlow, wHO was born in January, is “beyond amazing, and my family has been supportive. And I go to my dad’s house totally the time.”

Stallone considering more Rambo, Rocky sequels

Stallone considering more Rambo, Rocky sequels

Sylvester Stallone is considering scripts for further sequels in his 'Rocky' and 'Rambo' franchises, disdain vowing never to revive either of the legendary characters again.
The military action asterisk has signed a multimillion dollar apportion to address and asterisk in 2 freshly action films, which may feature his two best known characters.
The thespian will once again associate with 'Rambo' producers Danny Dimbort, Avi Lerner and Trevor Short of Nu Image/Millennium Films following the success of his recent films 'John Rambo' and 'Rocky Balboa'.
He told the Hollywood Newsperson: "The past tense year and a one-half of workings with Avi, his partners Danny and Trevor and his celluloid family line has been nil merely a high point for me and my life history and an super rewarding see. Avi is a real gentleman and a man of his bible."
Stallone's 2006 photographic film 'Rocky Balboa' grossed $70m, spell the quartern installation in the 'Rambo' enfranchisement took $18.2m in its opening weekend in the US last month.
The 61-year-old is likewise individually workings on a remake of the 1974 vigilante play 'Death Wish'.

kid yards lost offer

   
Artist: The Kraft

   Genre(s): 
Drum & Bass
   

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Discography:


   
 Feedback EP

   Year: 2001   
Tracks: 4


   
 Blade (2000)

   Year: 2000   
Tracks: 2


   
 Charge (CHRG002)

   Year: 1998   
Tracks: 2

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